Neuregulin 3 antibody
Quick Overview for Neuregulin 3 antibody (ABIN7191717)
Target
See all Neuregulin 3 (NRG3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of Human NRG3
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Isotype
- IgG
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Application Notes
- ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Neuregulin 3 (NRG3)
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Alternative Name
- NRG3
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Background
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Background: This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4.
Aliases: HRG3 antibody, Neuregulin 3 antibody, Neuregulin 3 like polypeptide antibody, Neuregulin-3 antibody, Neuregulin3 antibody, NRG-3 antibody, Nrg3 antibody, NRG3_HUMAN antibody, Pro neuregulin 3 antibody, pro NRG3 antibody, Pro-NRG3 antibody
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UniProt
- P56975
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Pathways
- RTK Signaling
Target
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