NAIP antibody (AA 1151-1250) (HRP)

Catalog No. ABIN715010

The Rabbit Polyclonal anti-NAIP antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect NAIP in samples from Human.

Quick Overview for NAIP antibody (AA 1151-1250) (HRP) (ABIN715010)

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAIP antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NAIP Antibody (HRP)

Binding Specificity: AA 1151-1250

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NAIP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NAIP

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Alternative Name: NAIP

Background:

Synonyms: Baculoviral IAP repeat containing 1, Baculoviral IAP repeat-containing protein 1, BIRC 1, BIRC1, BIRC1_HUMAN, Birc1a, NAIP, Naip1, Neuronal apoptosis inhibitory protein, NLR family apoptosis inhibitory protein, NLR family BIR domain containing 1, NLRB 1, NLRB1, Nucleotide binding oligomerization domain leucine rich repeat and BIR domain containing 1, Psi neuronal apoptosis inhibitory protein, psiNAIP, Similar to occludin.

Background: Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.

Gene ID: 4671

Pathways: Apoptosis, Inflammasome