Transportin 1 antibody

Catalog No. ABIN7192846

This Rabbit Polyclonal antibody specifically detects Transportin 1 in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Transportin 1 antibody (ABIN7192846)

Target: Transportin 1 (TNPO1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transportin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Transportin 1 Antibody

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of Human TNPO1

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Transportin 1

Target: Transportin 1 (TNPO1)

Alternative Name: TNPO1

Background:

Background: This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.

Aliases: Importin 2 antibody, Importin beta 2 antibody, Importin beta-2 antibody, IPO 2 antibody, IPO2 antibody, Karyopherin (importin) beta 2 antibody, Karyopherin beta 2 antibody, Karyopherin beta-2 antibody, KPN B2 antibody, KPNB 2 antibody, KPNB2 antibody, M9 interacting protein antibody, M9 region interacting protein antibody, M9 region interaction protein antibody, MIP 1 antibody, MIP antibody, MIP1 antibody, OTTHUMP00000126960 antibody, OTTHUMP00000222024 antibody, OTTHUMP00000226224 antibody, TNPO 1 antibody, Tnpo1 antibody, TNPO1_HUMAN antibody, Transportin 1 antibody, Transportin antibody, Transportin-1 antibody, Transportin1 antibody, TRN antibody

UniProt: Q92973

Pathways: PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events