CD97 antibody (AA 419-552)

Catalog No. ABIN7193255

Product Details anti-CD97 Antibody

Target: CD97

Binding Specificity: AA 419-552

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD97 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD97 (AA: extra 419-552) expressed in E. coli.

Clone: 6D7E6

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for CD97

Target: CD97

Alternative Name: CD97 (CD97 Products)

Synonyms: AA409984 antibody, TM7LN1 antibody, adhesion G protein-coupled receptor E5 antibody, Adgre5 antibody, ADGRE5 antibody

Background:

Description: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

Aliases: ADGRE5, TM7LN1

Molecular Weight: 91.8 kDa

Gene ID: 976