JAG1 antibody (AA 47-212)

Catalog No. ABIN7193264

The Mouse Monoclonal anti-JAG1 antibody has been validated for WB, ELISA and FACS. It is suitable to detect JAG1 in samples from Human.

Quick Overview for JAG1 antibody (AA 47-212) (ABIN7193264)

Target: JAG1 (Jagged 1 (JAG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 7C7H2

Product Details anti-JAG1 Antibody

Binding Specificity: AA 47-212

Purpose: CD339 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD339 (AA: 47-212) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: CD339

Background:

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Molecular Weight: 133.8 kDa

Gene ID: 182

UniProt: P78504

Pathways: Notch Signaling, Stem Cell Maintenance