KAT2B antibody (AA 1-142)

Catalog No. ABIN7193343

This anti-KAT2B antibody is a Mouse Monoclonal antibody detecting KAT2B in ELISA, IHC, FACS and ICC. Suitable for Human, Mouse, Rat and Monkey.

Quick Overview for KAT2B antibody (AA 1-142) (ABIN7193343)

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This KAT2B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 7D12C8

Product Details anti-KAT2B Antibody

Binding Specificity: AA 1-142

Purpose: KAT2B Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human KAT2B (AA: 1-142) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for KAT2B

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Alternative Name: KAT2B

Background:

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Molecular Weight: 93 kDa

UniProt: Q92831

Pathways: p53 Signaling, Regulation of Carbohydrate Metabolic Process