Poliovirus Receptor antibody (AA 21-343)

Catalog No. ABIN7193491

This Mouse Monoclonal antibody specifically detects Poliovirus Receptor in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for Poliovirus Receptor antibody (AA 21-343) (ABIN7193491)

Target: Poliovirus Receptor (PVR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Poliovirus Receptor antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 6D2D6

Product Details anti-Poliovirus Receptor Antibody

Binding Specificity: AA 21-343

Purpose: CD155 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD155 (AA: 21-343) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: CD155

Background:

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 45.3 kDa

Gene ID: 5817

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome