Poliovirus Receptor antibody (AA 21-343)

Catalog No. ABIN7092946

The Rabbit Monoclonal anti-Poliovirus Receptor antibody is suitable to detect Poliovirus Receptor in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for Poliovirus Receptor antibody (AA 21-343) (ABIN7092946)

Target: Poliovirus Receptor (PVR)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Poliovirus Receptor antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: DM146

Product Details anti-Poliovirus Receptor Antibody

Binding Specificity: AA 21-343

Purpose: Anti-CD155 antibody(DM146), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human CD155(Trp21-Asn343) (ABIN6961100) produced by using human HEK293 cells

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: CD155

Background: Synonyms:PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5
Description:The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 45.3KDa

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome