Poliovirus Receptor antibody (AA 21-343)

Catalog No. ABIN7193491

Product Details anti-Poliovirus Receptor Antibody

Target: Poliovirus Receptor (PVR)

Binding Specificity: AA 21-343

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Poliovirus Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human CD155 (AA: 21-343) expressed in E. coli.

Clone: 6D2D6

Isotype: IgG1

Application Details

Application Notes: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: CD155 (PVR Products)

Synonyms: PVR antibody, CD155 antibody, HVED antibody, NECL5 antibody, Necl-5 antibody, PVS antibody, TAGE4 antibody, 3830421F03Rik antibody, D7Ertd458e antibody, Taa1 antibody, Tage4 antibody, mE4 antibody, necl-5 antibody, poliovirus receptor antibody, PVR antibody, Pvr antibody

Background:

Description: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: PVR, PVS, HVED, NECL5, TAGE4, Necl-5

Molecular Weight: 45.3 kDa

Gene ID: 5817

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome