MSH2 antibody (AA 2-151)
Quick Overview for MSH2 antibody (AA 2-151) (ABIN7193789)
Target
See all MSH2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 2-151
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Purpose
- MSH2 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human MSH2 (AA: 2-151) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MSH2 (Mismatch Repair Protein 2 (MSH2))
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Alternative Name
- MSH2
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Background
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This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 104.7 kDa
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Gene ID
- 4436
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UniProt
- P43246
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Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
Target
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