MERTK antibody

Catalog No. ABIN7193794

This Mouse Monoclonal antibody specifically detects MERTK in WB, ELISA, FACS and ICC. It exhibits reactivity toward Human.

Quick Overview for MERTK antibody (ABIN7193794)

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MERTK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3D11G8

Product Details anti-MERTK Antibody

Purpose: MERTK Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MERTK (AA:extra(21-220)) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MERTK

Target: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Alternative Name: MERTK

Background:

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Molecular Weight: 140-180 kDa

UniProt: Q12866

Pathways: RTK Signaling