Endoglin antibody (AA 342-586)

Catalog No. ABIN7193820

This anti-Endoglin antibody is a Mouse Monoclonal antibody detecting Endoglin in WB, FACS, IHC and ELISA. Suitable for Human.

Quick Overview for Endoglin antibody (AA 342-586) (ABIN7193820)

Target: Endoglin (ENG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA

Clone: 2B2H2

Product Details anti-Endoglin Antibody

Binding Specificity: AA 342-586

Purpose: CD105 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD105 (AA: 342-586) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background:

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 70.6 kDa

UniProt: P17813