TARDBP antibody

Catalog No. ABIN7193979

The Mouse Monoclonal anti-TARDBP antibody (Clone 6G2D8) (ABIN7193979) specifically detects TARDBP in WB, IHC, ELISA, ICC and FACS. The antibody is reactive with Human samples.

Quick Overview for TARDBP antibody (ABIN7193979)

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TARDBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 6G2D8

Product Details anti-TARDBP Antibody

Purpose: TDP43 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TDP43 (AA: free peptide) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TARDBP

Target: TARDBP (TAR DNA Binding Protein (TARDBP))

Alternative Name: TDP43

Background:

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]

Molecular Weight: 44.7 kDa

Gene ID: 23435

Pathways: Positive Regulation of Peptide Hormone Secretion