Acrosin antibody (AA 40-120)
Quick Overview for Acrosin antibody (AA 40-120) (ABIN7212412)
Target
See all Acrosin (ACR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 40-120
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Purpose
- Acrosin Polyclonal Antibody
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Specificity
- Acrosin Polyclonal Antibody detects endogenous levels of Acrosin protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the N-terminal region of human Acrosin at AA range: 40-120
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Acrosin (ACR)
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Alternative Name
- Acrosin
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Background
- Rabbit Anti-Acrosin Polyclonal Antibody,ACR, ACRS, Acrosin,Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.,Acrosin
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Gene ID
- 49
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UniProt
- P10323
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Pathways
- cAMP Metabolic Process
Target
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