Actin, gamma 1 antibody

Catalog No. ABIN7227202

This Rabbit Polyclonal antibody specifically detects Actin, gamma 1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Actin, gamma 1 antibody (ABIN7227202)

Target: Actin, gamma 1 (ACTG1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Actin, gamma 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Actin, gamma 1 Antibody

Purpose: Rabbit Anti-ACTG Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ACTG protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ACTG protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Actin, gamma 1

Target: Actin, gamma 1 (ACTG1)

Alternative Name: ACTG

Background: Actin, cytoplasmic 2, Gamma-actinActins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by ACTG1, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight: 41kD

Gene ID: 71

UniProt: P63261

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization