Acox2 antibody (AA 270-350)

Catalog No. ABIN7227186

The Rabbit Polyclonal anti-Acox2 antibody (ABIN7227186) specifically detects Acox2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Acox2 antibody (AA 270-350) (ABIN7227186)

Target: Acox2 (Acyl-CoA Oxidase 2, Branched Chain (Acox2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acox2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Acox2 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-ACOX2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ACOX2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ACOX2 protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Acox2

Target: Acox2 (Acyl-CoA Oxidase 2, Branched Chain (Acox2))

Alternative Name: ACOX2

Background: Peroxisomal acyl-coenzyme A oxidase 2, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase, Trihydroxycoprostanoyl-CoA oxidase, THCA-CoA oxidase, THCCoxACOX2 (Acyl-CoA Oxidase 2) is a Protein Coding gene. Diseases associated with ACOX2 include Bile Acid Synthesis Defect, Congenital, 6 and Congenital Bile Acid Synthesis Defect. Among its related pathways are Metabolism and Synthesis of bile acids and bile salts. The product of ACOX2 belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children.

Molecular Weight: 74kD

Gene ID: 8309

UniProt: Q99424

Pathways: Monocarboxylic Acid Catabolic Process