ADAM8 antibody

Catalog No. ABIN7227214

The Rabbit Polyclonal anti-ADAM8 antibody (ABIN7227214) specifically detects ADAM8 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for ADAM8 antibody (ABIN7227214)

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADAM8 Antibody

Purpose: Rabbit Anti-ADAM8 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ADAM8 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ADAM8 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADAM8

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Alternative Name: ADAM8

Background: Disintegrin and metalloproteinase domain-containing protein 8, ADAM 8, Cell surface antigen MS2, CD_antigen: CD156aADAM8 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM Metallopeptidase Domain 8 encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

Molecular Weight: 90kD

Gene ID: 101

UniProt: P78325

Pathways: Activation of Innate immune Response, M Phase