ADCY1 antibody (AA 200-280)

Catalog No. ABIN7213394

The Rabbit Polyclonal anti-ADCY1 antibody is suitable to detect ADCY1 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for ADCY1 antibody (AA 200-280) (ABIN7213394)

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ADCY1 Antibody

Binding Specificity: AA 200-280

Purpose: Rabbit Anti-A Cyclase I Polyclonal Antibody

Specificity: A Cyclase I Polyclonal Antibody detects endogenous levels of A Cyclase I protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human A Cyclase I at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADCY1

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Alternative Name: A Cyclase I

Background: ADCY1, Adenylate cyclase type 1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, Ca(2+)/calmodulin-activated adenylyl cyclaseADCY1 encodes a member (adenylate cyclase 1) of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants.

Molecular Weight: 130kD

Gene ID: 107

UniProt: Q08828

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma