ADCY5/6 antibody (AA 900-980)

Catalog No. ABIN7213396

This anti-ADCY5/6 antibody is a Rabbit Polyclonal antibody detecting ADCY5/6 in ELISA, IF, WB and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for ADCY5/6 antibody (AA 900-980) (ABIN7213396)

Target: ADCY5/6 (Adenylate Cyclase 5/6 (ADCY5/6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY5/6 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADCY5/6 Antibody

Binding Specificity: AA 900-980

Purpose: A Cyclase V/VI Polyclonal Antibody

Specificity: A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human A Cyclase V/VI at AA range: 900-980

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ADCY5/6

Target: ADCY5/6 (Adenylate Cyclase 5/6 (ADCY5/6))

Alternative Name: A Cyclase V/VI

Background: Rabbit Anti-A Cyclase V/VI Polyclonal Antibody,ADCY5, Adenylate cyclase type 5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY6, KIAA0422, Adenylate cyclase type 6, ATP pyrophosphate-lyase 6, Adenylate cyclase type VI, Adenylyl cyclase 6, Ca(2+)-inhibitabl,ADCY5 encodes a member (adenylate cyclase 5) of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5.,Adenylate cyclase type 5

Gene ID: 111, 112