ADCY7 antibody (AA 160-240)

Catalog No. ABIN7219310

The Rabbit Polyclonal anti-ADCY7 antibody is suitable to detect ADCY7 in samples from Human and Mouse. It has been validated for IHC, ELISA and IF.

Quick Overview for ADCY7 antibody (AA 160-240) (ABIN7219310)

Target: ADCY7 (Adcy7) (Adenylate Cyclase 7 (Adcy7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-ADCY7 Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-A Cyclase VII Polyclonal Antibody

Specificity: A Cyclase VII Polyclonal Antibody detects endogenous levels of A Cyclase VII protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human A Cyclase VII at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADCY7

Target: ADCY7 (Adcy7) (Adenylate Cyclase 7 (Adcy7))

Alternative Name: A Cyclase VII

Background: ADCY7, KIAA0037, Adenylate cyclase type 7, ATP pyrophosphate-lyase 7, Adenylate cyclase type VII, Adenylyl cyclase 7ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far.

Gene ID: 113

UniProt: P51828

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma