ARFGAP1 antibody (AA 140-220)
Quick Overview for ARFGAP1 antibody (AA 140-220) (ABIN7223470)
Target
See all ARFGAP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 140-220
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Purpose
- ARF GAP1 Polyclonal Antibody
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Specificity
- ARF GAP1 Polyclonal Antibody detects endogenous levels of ARF GAP1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human ARF GAP1 at AA range: 140-220
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
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Alternative Name
- ARF GAP1
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Background
- Rabbit Anti-ARF GAP1 Polyclonal Antibody,ARFGAP1, ARF1GAP, ADP-ribosylation factor GTPase-activating protein 1, ARF GAP 1, ADP-ribosylation factor 1 GTPase-activating protein, ARF1 GAP, ARF1-directed GTPase-activating protein,The protein encoded by ARFGAP1 (ADP ribosylation factor GTPase activating protein 1) is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.,ADP-ribosylation factor GTPase-activating protein 1
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Gene ID
- 55738
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UniProt
- Q8N6T3
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Pathways
- p53 Signaling, ER-Nucleus Signaling, Unfolded Protein Response
Target
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