AFG3L2 antibody (AA 744-793)

Catalog No. ABIN7227232

The Rabbit Polyclonal anti-AFG3L2 antibody (ABIN7227232) specifically detects AFG3L2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for AFG3L2 antibody (AA 744-793) (ABIN7227232)

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFG3L2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AFG3L2 Antibody

Binding Specificity: AA 744-793

Purpose: Rabbit Anti-AFG3L2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AFG3L2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AFG3L2 protein at AA range: 744-793

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Alternative Name: AFG3L2

Background: AFG3-like protein 2, Paraplegin-like proteinAFG3L2 (AFG3 Like Matrix AAA Peptidase Subunit 2) is a Protein Coding gene. Diseases associated with AFG3L2 include Spinocerebellar Ataxia 28 and Spastic Ataxia 5, Autosomal Recessive. AFG3L2 encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.

Molecular Weight: 88kD

Gene ID: 10939

UniProt: Q9Y4W6

Pathways: Skeletal Muscle Fiber Development