AES antibody

Catalog No. ABIN7227228

This Rabbit Polyclonal antibody specifically detects AES in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AES antibody (ABIN7227228)

Target: AES (Amino-terminal Enhancer of Split (AES))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AES antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AES Antibody

Purpose: Rabbit Anti-AES Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AES protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AES protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AES

Target: AES (Amino-terminal Enhancer of Split (AES))

Alternative Name: AES

Background: Amino-terminal enhancer of split, Amino enhancer of split, Gp130-associated protein GAM, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRGAmino-Terminal Enhancer Of Split encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 21kD

Gene ID: 166

UniProt: Q08117

Pathways: WNT Signaling, SARS-CoV-2 Protein Interactome