AASS antibody (AA 220-300)

Catalog No. ABIN7213406

This Rabbit Polyclonal antibody specifically detects AASS in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AASS antibody (AA 220-300) (ABIN7213406)

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AASS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AASS Antibody

Binding Specificity: AA 220-300

Purpose: Rabbit Anti-AASS Polyclonal Antibody

Specificity: AASS Polyclonal Antibody detects endogenous levels of AASS protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human AASS at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AASS

Target: AASS (Aminoadipate Semialdehyde Synthase (AASS))

Alternative Name: AASS

Background: AASS, Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDHAASS encodes a bifunctional enzyme (aminoadipate-semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.

Molecular Weight: 102kD

Gene ID: 10157

UniProt: Q9UDR5

Pathways: SARS-CoV-2 Protein Interactome