ALS2 antibody (AA 390-470)

Catalog No. ABIN7227272

The Rabbit Polyclonal anti-ALS2 antibody (ABIN7227272) specifically detects ALS2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ALS2 antibody (AA 390-470) (ABIN7227272)

Target: ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ALS2 Antibody

Binding Specificity: AA 390-470

Purpose: Rabbit Anti-ALS2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ALS2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ALS2 protein at AA range: 390-470

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ALS2

Target: ALS2 (Amyotrophic Lateral Sclerosis 2 (Juvenile) (ALS2))

Alternative Name: ALS2

Background: Alsin, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein, Amyotrophic lateral sclerosis 2 proteinALS2 (ALS2, Alsin Rho Guanine Nucleotide Exchange Factor) is a Protein Coding gene. Diseases associated with ALS2 include Primary Lateral Sclerosis, Juvenile and Spastic Paralysis, Infantile Onset Ascending. Among its related pathways are RAB GEFs exchange GTP for GDP on RABs and Vesicle-mediated transport.

Molecular Weight: 182kD

Gene ID: 57679

UniProt: Q96Q42

Pathways: Skeletal Muscle Fiber Development