APOC3 antibody (C-Term)

Catalog No. ABIN7218606

This Rabbit Polyclonal antibody specifically detects APOC3 in WB, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for APOC3 antibody (C-Term) (ABIN7218606)

Target: APOC3 (Apolipoprotein C-III (APOC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-APOC3 Antibody

Binding Specificity: C-Term

Purpose: ApoC-III Polyclonal Antibody

Specificity: ApoC-III Polyclonal Antibody detects endogenous levels of ApoC-III protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human ApoC-III

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for APOC3

Target: APOC3 (Apolipoprotein C-III (APOC3))

Alternative Name: ApoC-III

Background: Rabbit Anti-ApoC-III Polyclonal Antibody,APOC3, Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3,Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase, it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.,Apolipoprotein C-III

Gene ID: 345

UniProt: P02656

Pathways: Carbohydrate Homeostasis, Lipid Metabolism