AATK antibody (AA 1110-1190)

Catalog No. ABIN7229418

The Rabbit Polyclonal anti-AATK antibody (ABIN7229418) specifically detects AATK in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for AATK antibody (AA 1110-1190) (ABIN7229418)

Target: AATK (Apoptosis-Associated tyrosine Kinase (AATK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AATK antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-AATK Antibody

Binding Specificity: AA 1110-1190

Purpose: Rabbit Anti-LMTK1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LMTK1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LMTK1 protein at AA range: 1110-1190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AATK

Target: AATK (Apoptosis-Associated tyrosine Kinase (AATK))

Alternative Name: LMTK1

Background: Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BPThe protein encoded by AATK contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of AATK may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. AATK has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for AATK.

Molecular Weight: 151kD

Gene ID: 9625

UniProt: Q6ZMQ8

Pathways: RTK Signaling, Regulation of Cell Size