Aprataxin antibody (AA 11-60)

Catalog No. ABIN7227342

This Rabbit Polyclonal antibody specifically detects Aprataxin in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Aprataxin antibody (AA 11-60) (ABIN7227342)

Target: Aprataxin (APTX)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aprataxin antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Aprataxin Antibody

Binding Specificity: AA 11-60

Purpose: Rabbit Anti-APTX Polyclonal Antibody

Specificity: The antibody detects endogenous levels of APTX protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human APTX protein at AA range: 11-60

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Aprataxin

Target: Aprataxin (APTX)

Alternative Name: APTX

Background: Aprataxin, Forkhead-associated domain histidine triad-like protein, FHA-HITAPTX encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in APTX have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for APTX.

Molecular Weight: 39kD

Gene ID: 54840

UniProt: Q7Z2E3

Pathways: DNA Damage Repair, Chromatin Binding