AGFG2 antibody (AA 60-140)

Catalog No. ABIN7221566

The Rabbit Polyclonal anti-AGFG2 antibody is suitable to detect AGFG2 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for AGFG2 antibody (AA 60-140) (ABIN7221566)

Target: AGFG2 (ArfGAP with FG Repeats 2 (AGFG2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGFG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-AGFG2 Antibody

Binding Specificity: AA 60-140

Purpose: Rabbit Anti-Rabr Polyclonal Antibody

Specificity: Rabr Polyclonal Antibody detects endogenous levels of Rabr protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Rabr at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AGFG2

Target: AGFG2 (ArfGAP with FG Repeats 2 (AGFG2))

Alternative Name: Rabr

Background: AGFG2, HRBL, RABR, Arf-GAP domain and FG repeat-containing protein 2, HIV-1 Rev-binding protein-like protein, Rev/Rex activation domain-binding protein related, RAB-RAGFG2 is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. ArfGAP with FG repeats 2 interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Molecular Weight: 49kD

Gene ID: 3268

UniProt: O95081