AVPR1B antibody (AA 271-320)

Catalog No. ABIN7227432

The Rabbit Polyclonal anti-AVPR1B antibody is suitable to detect AVPR1B in samples from Human, Rat and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for AVPR1B antibody (AA 271-320) (ABIN7227432)

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-AVPR1B Antibody

Binding Specificity: AA 271-320

Purpose: Rabbit Anti-AVP Receptor V3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AVP Receptor V3

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AVP Receptor V3 protein at AA range: 271-320

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Alternative Name: AVP Receptor V3

Background: Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptorThe protein encoded by AVP Receptor acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript ofAVP Receptor has been reported but its function is not known.

Gene ID: 553

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones