ARR3 antibody (AA 320-400)

Catalog No. ABIN7222280

The Rabbit Polyclonal anti-ARR3 antibody (ABIN7222280) specifically detects ARR3 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ARR3 antibody (AA 320-400) (ABIN7222280)

Target: ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ARR3 Antibody

Binding Specificity: AA 320-400

Purpose: Rabbit Anti-Arrestin-C Polyclonal Antibody

Specificity: Arrestin-C Polyclonal Antibody detects endogenous levels of Arrestin-C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Arrestin-C at AA range: 320-400

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ARR3

Target: ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))

Alternative Name: Arrestin-C

Background: ARR3, ARRX, CAR, Arrestin-C, Cone arrestin, C-arrestin, cArr, Retinal cone arrestin-3, X-arrestinThe protein encoded by ARR3 is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function.

Molecular Weight: 40kD

Gene ID: 407

UniProt: P36575

Pathways: Phototransduction, Thromboxane A2 Receptor Signaling