Aryl Hydrocarbon Receptor antibody

Catalog No. ABIN7213504

The Rabbit Polyclonal anti-Aryl Hydrocarbon Receptor antibody (ABIN7213504) specifically detects Aryl Hydrocarbon Receptor in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Aryl Hydrocarbon Receptor antibody (ABIN7213504)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Aryl Hydrocarbon Receptor Antibody

Purpose: Rabbit Anti-Ah Receptor Polyclonal Antibody

Specificity: Ah Receptor Polyclonal Antibody detects endogenous levels of Ah Receptor protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Ah Receptor around the non-phosphorylation site of S36

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: Ah Receptor

Background: AHR, BHLHE76, Aryl hydrocarbon receptor, Ah receptor, AhR, Class E basic helix-loop-helix protein 76, bHLHe76, AHRR, BHLHE77, KIAA1234, Aryl hydrocarbon receptor repressor, AhR repressor, AhRR, Class E basic helix-loop-helix protein 77, bHLAryl hydrocarbon receptor encoded by AHR is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm, upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.

Molecular Weight: 75kD or 96kD

Gene ID: 196, 57491

UniProt: P35869, A9YTQ3

Pathways: Regulation of Cell Size