Ataxin 10 antibody (AA 10-90)
Quick Overview for Ataxin 10 antibody (AA 10-90) (ABIN7227426)
Target
See all Ataxin 10 (ATXN10) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 10-90
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Purpose
- Rabbit Anti-ATX10 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of ATX10 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human ATX10 protein at AA range: 10-90
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- Ataxin 10 (ATXN10)
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Alternative Name
- ATX10
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Background
- Ataxin-10, Brain protein E46 homolog, Spinocerebellar ataxia type 10 proteinATXN10 encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
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Molecular Weight
- 52kD
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Gene ID
- 25814
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UniProt
- Q9UBB4
Target
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