ATG16L1 antibody (AA 60-140)

Catalog No. ABIN7223368

The Rabbit Polyclonal anti-ATG16L1 antibody (ABIN7223368) specifically detects ATG16L1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for ATG16L1 antibody (AA 60-140) (ABIN7223368)

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG16L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ATG16L1 Antibody

Binding Specificity: AA 60-140

Purpose: Rabbit Anti-Atg16 Polyclonal Antibody

Specificity: Atg16 Polyclonal Antibody detects endogenous levels of Atg16 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Atg16 at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ATG16L1

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Alternative Name: Atg16

Background: ATG16L1, APG16L, Autophagy-related protein 16-1, APG16-like 1The protein encoded by ATG16L1 (autophagy related 16 like 1) is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in ATG16L1 are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for ATG16L1.

Molecular Weight: 70kD

Gene ID: 55054

UniProt: Q676U5

Pathways: Autophagy