ATRIP antibody

Catalog No. ABIN7213734

This Rabbit Polyclonal antibody specifically detects ATRIP in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ATRIP antibody (ABIN7213734)

Target: ATRIP (ATR Interacting Protein (ATRIP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATRIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ATRIP Antibody

Purpose: Rabbit Anti-ATRIP Polyclonal Antibody

Specificity: ATRIP Polyclonal Antibody detects endogenous levels of ATRIP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human ATRIP around the non-phosphorylation site of S68

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ATRIP

Target: ATRIP (ATR Interacting Protein (ATRIP))

Alternative Name: ATRIP

Background: ATRIP, AGS1, ATR-interacting protein, ATM and Rad3-related-interacting proteinATRIP encodes an essential component of the DNA damage checkpoint. The encoded protein (ATR interacting protein) binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

Molecular Weight: 80kD

Gene ID: 84126

UniProt: Q8WXE1