ATG10 antibody (AA 1-50)

Catalog No. ABIN7227398

The Rabbit Polyclonal anti-ATG10 antibody is suitable to detect ATG10 in samples from Human and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for ATG10 antibody (AA 1-50) (ABIN7227398)

Target: ATG10 (Autophagy Related 10 (ATG10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG10 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ATG10 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit Anti-ATG10 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ATG10

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ATG10 protein at AA range: 1-50

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ATG10

Target: ATG10 (Autophagy Related 10 (ATG10))

Alternative Name: ATG10

Background: Ubiquitin-like-conjugating enzyme ATG10, Autophagy-related protein 10, APG10-likeAutophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: aTG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A, MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al. 2003 ATG10 (Autophagy Related 10) is a Protein Coding gene. Diseases associated with ATG10 include Anthracosis. Among its related pathways are Cellular Senescence (REACTOME) and Autophagy Pathway.

Gene ID: 83734

UniProt: Q9H0Y0

Pathways: ER-Nucleus Signaling, Autophagy