BMP8A antibody (AA 230-310)

Catalog No. ABIN7213826

The Rabbit Polyclonal anti-BMP8A antibody is suitable to detect BMP8A in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for BMP8A antibody (AA 230-310) (ABIN7213826)

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP8A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-BMP8A Antibody

Binding Specificity: AA 230-310

Purpose: Rabbit Anti-BMP-8A Polyclonal Antibody

Specificity: BMP-8A Polyclonal Antibody detects endogenous levels of BMP-8A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human BMP-8A at AA range: 230-310

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BMP8A

Target: BMP8A (Bone Morphogenetic Protein 8A (BMP8A))

Alternative Name: BMP-8A

Background: BMP8A, Bone morphogenetic protein 8A, BMP-8ABMP8A encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. BMP8A may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.

Molecular Weight: 45-55kD

Gene ID: 353500

UniProt: Q7Z5Y6

Pathways: Negative Regulation of Hormone Secretion