CTBP1 antibody (pSer422)

Catalog No. ABIN7219802

The Rabbit Polyclonal anti-CTBP1 antibody is suitable to detect CTBP1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for CTBP1 antibody (pSer422) (ABIN7219802)

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CTBP1 Antibody

Binding Specificity: pSer422

Purpose: Rabbit Anti-CtBP1 (phospho Ser422) Polyclonal Antibody

Specificity: Phospho-CtBP1 (S422) Polyclonal Antibody detects endogenous levels of CtBP1 protein only when phosphorylated at S422.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CtBP1 Phospho-Ser422

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CTBP1

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Alternative Name: CtBP1

Background: CTBP1, CTBP, C-terminal-binding protein 1, CtBP1CTBP1 encodes C-terminal binding protein 1 that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

Molecular Weight: 48kD

Gene ID: 1487

UniProt: Q13363

Pathways: Retinoic Acid Receptor Signaling Pathway