CDH23 antibody (AA 30-110)

Catalog No. ABIN7224214

This Rabbit Polyclonal antibody specifically detects CDH23 in ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CDH23 antibody (AA 30-110) (ABIN7224214)

Target: CDH23 (Cadherin 23 (CDH23))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDH23 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-CDH23 Antibody

Binding Specificity: AA 30-110

Purpose: Cadherin-23 Polyclonal Antibody

Specificity: Cadherin-23 Polyclonal Antibody detects endogenous levels of Cadherin-23 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Cadherin-23 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CDH23

Target: CDH23 (Cadherin 23 (CDH23))

Alternative Name: Cadherin-23

Background: Rabbit Anti-Cadherin-23 Polyclonal Antibody,CDH23, KIAA1774, KIAA1812, Cadherin-23, Otocadherin,CDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of CDH23 may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.,Cadherin-23

Gene ID: 64072

UniProt: Q9H251

Pathways: Sensory Perception of Sound