CDH23 antibody (C-Term)

Catalog No. ABIN7189385

Product Details anti-CDH23 Antibody

Target: CDH23 (Cadherin 23 (CDH23))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDH23 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen Affinity Purified

Immunogen: Synthetic peptide corresponding to residues near the C terminal of Human pan-cadherin

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in pH 7.3 PBS, 0.05 % Sodium azide, 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDH23

Target: CDH23 (Cadherin 23 (CDH23))

Alternative Name: CDH23 (CDH23 Products)

Synonyms: 4930542A03Rik antibody, USH1D antibody, ahl antibody, ahl1 antibody, bob antibody, bus antibody, mdfw antibody, nmf112 antibody, nmf181 antibody, nmf252 antibody, sals antibody, v antibody, CDHR23 antibody, W antibody, cadherin 23 (otocadherin) antibody, cadherin related 23 antibody, cadherin-related 23 antibody, Cdh23 antibody, CDH23 antibody

Background:

Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Aliases: CDH23 antibody, KIAA1774 antibody, KIAA1812 antibody, UNQ1894/PRO4340Cadherin-23 antibody, Otocadherin antibody

UniProt: Q9H251

Pathways: Sensory Perception of Sound