CEACAM3/6 antibody (Internal Region)

Catalog No. ABIN7218692

The Rabbit Polyclonal anti-CEACAM3/6 antibody is suitable to detect CEACAM3/6 in samples from Human and Rat. It has been validated for WB and ELISA.

Quick Overview for CEACAM3/6 antibody (Internal Region) (ABIN7218692)

Target: CEACAM3/6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3/6 (CEACAM3/6))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM3/6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CEACAM3/6 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CD66c/d Polyclonal Antibody

Specificity: CD66c/d Polyclonal Antibody detects endogenous levels of CD66c/d protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD66c/d

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CEACAM3/6

Target: CEACAM3/6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3/6 (CEACAM3/6))

Alternative Name: CD66c/d

Background: CEACAM3, CD66D, CGM1, Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM6, NCA, Carcinoembryonic antigen-related cell adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antigCEACAM3 encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The carcinoembryonic antigen related cell adhesion molecule 3 directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.

Molecular Weight: 30kD

Gene ID: 1084, 4680

UniProt: P40198, P40199