CEACAM3/6 antibody (AA 31-80)

Catalog No. ABIN8120201

This Rabbit Polyclonal antibody specifically detects CEACAM3/6 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CEACAM3/6 antibody (AA 31-80) (ABIN8120201)

Target: CEACAM3/6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3/6 (CEACAM3/6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM3/6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CEACAM3/6 Antibody

Binding Specificity: AA 31-80

Purpose: CD66c/d Antibody

Specificity: CD66c/d Polyclonal Antibody detects endogenous levels of CD66c/d protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CEACAM3/CEACAM6. AA range:31-80

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CEACAM3/6

Target: CEACAM3/6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3/6 (CEACAM3/6))

Alternative Name: CD66c/d

Background:

Synonyms: CEACAM3, CD66D, CGM1, Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM6, NCA, Carcinoembryonic antigen-related cell adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antigen, CD66c

Background: This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013],

Gene Name: CEACAM3/CEACAM6

Protein Name: Carcinoembryonic antigen-related cell adhesion molecule 3/Carcinoembryonic antigen-related cell adhesion molecule 6

Gene ID: 1084

UniProt: P40198