CEACAM5 antibody (Internal Region)

Catalog No. ABIN7217888

The Rabbit Polyclonal anti-CEACAM5 antibody (ABIN7217888) specifically detects CEACAM5 in IF, IHC, WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CEACAM5 antibody (Internal Region) (ABIN7217888)

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM5 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-CEACAM5 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CD66e Polyclonal Antibody

Specificity: CD66e Polyclonal Antibody detects endogenous levels of CD66e protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD66e

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CEACAM5

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Alternative Name: CD66e

Background: CEACAM5, CEA, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66eCEACAM5 encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The carcinoembryonic antigen related cell adhesion molecule 5 is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.

Molecular Weight: 76kD

Gene ID: 1048

UniProt: P06731