Cardiotrophin 1 antibody (AA 151-200)

Catalog No. ABIN7227598

The Rabbit Polyclonal anti-Cardiotrophin 1 antibody is suitable to detect Cardiotrophin 1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Cardiotrophin 1 antibody (AA 151-200) (ABIN7227598)

Target: Cardiotrophin 1 (CTF1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cardiotrophin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cardiotrophin 1 Antibody

Binding Specificity: AA 151-200

Purpose: Rabbit Anti-Cardiotrophin-1 Polyclonal Antibody

Specificity: This antibody detects endogenous levels of Cardiotrophin-1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Cardiotrophin-1 protein at AA range: 151-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cardiotrophin 1

Target: Cardiotrophin 1 (CTF1)

Alternative Name: Cardiotrophin-1

Background: Cardiotrophin-1, CT-1CTF1 (Cardiotrophin 1) is a Protein Coding gene. Diseases associated with CTF1 include Neonatal Stroke and Hypertensive Heart Disease. Among its related pathways are Jak-STAT signaling pathway (KEGG) and NFAT and Cardiac Hypertrophy. The protein encoded by CTF1 is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for CTF1.

Molecular Weight: 23kD

Gene ID: 1489

UniProt: Q16619

Pathways: JAK-STAT Signaling