CARTPT antibody

Catalog No. ABIN7227602

The Rabbit Polyclonal anti-CARTPT antibody is suitable to detect CARTPT in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for CARTPT antibody (ABIN7227602)

Target: CARTPT (CART Prepropeptide (CARTPT))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARTPT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CARTPT Antibody

Purpose: Rabbit Anti-CART Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CART protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CART protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CARTPT

Target: CARTPT (CART Prepropeptide (CARTPT))

Alternative Name: CART

Background: Cocaine- and amphetamine-regulated transcript proteinCARTPT encodes CART Prepropeptide that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans.

Molecular Weight: 12kD

Gene ID: 9607

UniProt: Q16568

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Feeding Behaviour