CCRN4L antibody (AA 100-180)

Catalog No. ABIN7230044

The Rabbit Polyclonal anti-CCRN4L antibody is suitable to detect CCRN4L in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for CCRN4L antibody (AA 100-180) (ABIN7230044)

Target: CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCRN4L antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCRN4L Antibody

Binding Specificity: AA 100-180

Purpose: Rabbit Anti-NOCT Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NOCT protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NOCT protein at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCRN4L

Target: CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))

Alternative Name: NOCT

Background: Nocturnin, Carbon catabolite repression 4-like protein, Circadian deadenylase NOCNOCT (Nocturnin) is a Protein Coding gene. Among its related pathways are Cyclins and Cell Cycle Regulation and Circadian rythm related genes. An important paralog of this gene is ANGEL1. The protein encoded by NOCT is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector.

Molecular Weight: 47kD

Gene ID: 25819

UniProt: Q9UK39

Pathways: Ribonucleoprotein Complex Subunit Organization