CD109 antibody (AA 751-800)

Catalog No. ABIN7227682

The Rabbit Polyclonal anti-CD109 antibody (ABIN7227682) specifically detects CD109 in IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for CD109 antibody (AA 751-800) (ABIN7227682)

Target: CD109

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD109 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CD109 Antibody

Binding Specificity: AA 751-800

Purpose: Rabbit Anti-CD109 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD109

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD109 protein at AA range: 751-800

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD109

Target: CD109

Alternative Name: CD109

Background: CD109 antigen, 150 kDa TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, Platelet-specific Gov antigen, p180, r150, CD antigen CD109CD109 encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for CD109. CD109 (CD109 Molecule) is a Protein Coding gene. Diseases associated with CD109 include Fetal And Neonatal Alloimmune Thrombocytopenia and Epithelioid Sarcoma. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Metabolism of proteins.

Gene ID: 135228

UniProt: Q6YHK3

Pathways: Activated T Cell Proliferation