CD6 antibody (AA 220-300)

Catalog No. ABIN7225892

This Rabbit Polyclonal antibody specifically detects CD6 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for CD6 antibody (AA 220-300) (ABIN7225892)

Target: CD6

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD6 Antibody

Binding Specificity: AA 220-300

Purpose: Rabbit Anti-CD6 Polyclonal Antibody

Specificity: CD6 Polyclonal Antibody detects endogenous levels of CD6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD6 at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD6

Target: CD6

Alternative Name: CD6

Background: CD6, T-cell differentiation antigen CD6, T12, TP120, CD antigen CD6CD6 (CD6 Molecule) encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. CD6 product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for CD6.

Molecular Weight: 73kD

Gene ID: 923

UniProt: P30203