CIDEC antibody (AA 160-240)

Catalog No. ABIN7224202

This Rabbit Polyclonal antibody specifically detects CIDEC in IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CIDEC antibody (AA 160-240) (ABIN7224202)

Target: CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIDEC antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CIDEC Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-CIDE-3 Polyclonal Antibody

Specificity: CIDE-3 Polyclonal Antibody detects endogenous levels of CIDE-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human CIDE-3 at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CIDEC

Target: CIDEC (Cell Death-Inducing DFFA-Like Effector C (CIDEC))

Alternative Name: CIDE-3

Background: CIDEC, FSP27, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27 homologCIDEC (cell death inducing DFFA like effector c) encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. CIDEC is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in CIDEC may contribute to insulin resistant diabetes. A pseudogene of CIDEC is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for CIDEC.

Gene ID: 63924

UniProt: Q96AQ7