CDC23 antibody (AA 220-300)

Catalog No. ABIN7214098

The Rabbit Polyclonal anti-CDC23 antibody (ABIN7214098) specifically detects CDC23 in WB and ELISA. The antibody is reactive with Human, Mouse and Monkey samples.

Quick Overview for CDC23 antibody (AA 220-300) (ABIN7214098)

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDC23 Antibody

Binding Specificity: AA 220-300

Purpose: Rabbit Anti-Cdc23 Polyclonal Antibody

Specificity: Cdc23 Polyclonal Antibody detects endogenous levels of Cdc23 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Cdc23 at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDC23

Target: CDC23 (Cell Division Cycle 23 (CDC23))

Alternative Name: Cdc23

Background: CDC23, ANAPC8, Cell division cycle protein 23 homolog, Anaphase-promoting complex subunit 8, APC8, Cyclosome subunit 8Cell division cycle 23 encoded by CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Molecular Weight: 69kD

Gene ID: 8697

UniProt: Q9UJX2

Pathways: Protein targeting to Nucleus